The Fifth Avenue Hotel, across from Madison Square Park, following an 1899 snowstorm.

"The Fifth-Avenue Hotel has borne a conspicuous part in the public life of the metropolis, and has been identified with the most notable local events of the generation since its opening, in 1859. The house fronts upon Madison Square, the most charming of the smaller parks of the city, at the junction of Broadway and Fifth Avenue the two great thoroughfares. It is unequalled in the number and spaciousness of its corridors, halls, and public rooms, and the commodious character of its guest rooms." This description by King's Handbook of New York (1893) demonstrates The Fifth Avenue Hotel's luxurious reputation. When Amos Eno built the hotel in 1859, the neighborhood was still dominated by town houses and it was thought to be so far uptown that it was called "Eno's Folly." Luxurious touches including a fireplace in every bedroom, private bathrooms, lavish public rooms, an Otis elevator and four hundred servants and fifty conveyances standing ready to serve the hotel's 800 guests, compensated for its location and assured its success.

The hotel was razed in 1908, ahead of the construction of the Toy Center Building on the same site.