Built in 1900 by Oscar Hammerstein I, the Republic was taken over in 1902 by David Belasco. The theater reverted to its original name around 1910 and continued as a legitimate house until 1932 when it became home to Billy Minsky's burlesque shows. After Mayor Fiorello LaGuardia banned burlesque in 1942, the Republic was converted into a movie theater, the Victory, and fell into decline. In 1995 the beautifully restored New Victory opened again as a theater.

The American Theatre, designed by Charles C. Haight, opened on May 22, 1893, with The Prodigal Daughter. T. Henry French, the manager, was one of the country's foremost producers, specializing in lavishly mounted extravaganzas. In 1897, French lost control of the theater in a foreclosure judgement, and it was taken over and used for every sort of entertainment; its last tenants being a burlesque troupe. Damaged by fire in 1930, the theater was razed to make way for other commercial structures.

One of almost ninety theater buildings documented by Byron, the Majestic's first year-1903- was a tremendous success, with such popular productions as The Wizard of Oz and Babes in Toyland. Located at Columbus Circle, not far from the current location of Lincoln Center for the Performing Arts, it was the northernmost Broadway house at the time. Sadly, it was too far from the theater district and within five years motion pictures- not theater- were the mainstay here. Despite attempts by the Shuberts, Florenz Ziegfeld and the Minsky family to revive the Majestic with legitimate theater, it continued to decline, and in 1954 it was demolished for wider pedestrian access to the equally unsuccessful New York Coliseum. In 1998 a plan to redevelop the site with a glass-and-steel tower was approved.

The Empire Theatre was built by Al Hayman and Frank W. Sanger for Charles Frogman, the architects were John B. McElfatrick and Son. Opening on January 25, 1893, the Empire remained one of New York's favorite theaters until the final performance on May 30, 1953, of The Time of the Cuckoo. An office building was later erected on this site.

The Casino Theatre was designed by Francis H. Kimball and Thomas Wisedel in a Gothic style. It was the home of musical comedies and housed the famous Gilbert and Sullivan attractions. The theater fell to the wreckers' ball in 1930.

Built by Ned Harrigan in 1890 and named the Harrigan Theatre, the venue was taken over in 1895 by Richard Mansfield, who changed its name to the Garrick. Mansfield leased it to Charles Frogman, who managed it until his death in 1915, when it was sold at auction. It became the home of the Theatre Guild, and after the Guild relocated it became a burlesque house. Severely damaged by fire in 12932, it was demolished as a safety hazard.

Built in 1883 as the New Park Theatre, and containing most of the interior fittings from the Booth Theatre, this playhouse was not successful until 1894 when it booked the Richard Mansfield Company and changed its name to the Herald Square Theatre. It turned to movies in 1912, was sold in 1914, and was torn down to make way for a garment industry building.

Between 1899 and 2002, the northwest corner o Seventh and 42nd Street was occupied by a theatre (with various reputable and less reputable productions). First, Oscar Hammerstein's massive Victoria Theatre presented legitimate theatre before turning—very successfully— to vaudeville. That theatre closed and was demolished in 1915. In 1916 a new theatre building on the site opened. The Rialto sat 1,960 patrons. The venue was exclusively a motion picture house, becoming one of midtown's best-known movie palaces. Paramount sold the building in 1935, and the new owners razed the venue. In its place, a new building with stores, offices, and a smaller theatre, also called the Rialto, rose. That theatre showed films but by the 1970s was screening movies of an adult nature.

Koster & Bial's, located at 34th Street and Broadway, on the current site of Macy's department store, was New York's other major vaudeville house in 1898. Built by Oscar Hammerstein in 1892, this was the first theater to bear the name Manhattan Opera House. Hammerstein offered Koster and Bial a partnership if they would take over this theater. The partnership was not a success and, after a succession of managers, the theater was closed in 1901. Offering more of a stag atmosphere, with drinking available on the premises, it attracted many of the top names in variety.

Koster & Bial's, located at 34th Street and Broadway, on the current site of Macy's department store, was New York's other major vaudeville house in 1898. Built by Oscar Hammerstein in 1892, this was the first theater to bear the name Manhattan Opera House. Hammerstein offered Koster and Bial a partnership if they would take over this theater. The partnership was not a success and, after a succession of managers, the theater was closed in 1901. Offering more of a stag atmosphere, with drinking available on the premises, it attracted many of the top names in variety.

Leased to Weber & Fields in 1896, this hall became one of New York's most popular places of entertainment. When the comedians temporarily dissolved their partnership in 1906, it was renamed Weber's theater. In 1912, it became a motion picture theater and was razed in 1917. An office building was erected on the site.

Occupying an entire block on 6th Avenue, with a seating capacity of 5200, the Hippodrome (which opened in 1905) was outfitted on a grand scale. The stage was 200 feet wide and 100 feet deep (large enough for the jai-alai exhibition games played there). It had an 60-foot apron which could be filled with water for aquatic productions. Behind the scenes, hydraulic machines raised and lowered the stage, and an indoor stable housed horses and elephants for circus productions. Such spectacles were so expensive to produce that the theater failed financially and closed in the late 1930s.

Opened originally as the Eagle Variety Theatre, this hall became a variety house in and was later renamed the Standard theatre. Achieving its greatest success as the Manhattan Theatre, the venue hosted some of the most famous actors and companies of the day. In 1906, it was one of the first legitimate theaters to be taken over by movies.

The Lyceum Theatre on 45th Street, which opened November 2, 1903 is the oldest continuously operating playhouse in Times Square Theatre District . Though the New Amsterdam Theatre and the Hudson Theatre opened earlier that same year, both spaces flirted with careers as movie theaters. The Lyceum holds the distinction of being the District’s oldest continually play-producing theatre, and in 1974, it was the first Broadway theater to be landmarked.